Clinical application of the RONNA G4 system – preliminary validation of 23 robotic frameless brain biopsies

Znanstveni rad - Izvorni znanstveni rad

• Autor: Domagoj Dlaka
• Autor: Marko Švaco
• Autor: Darko Chudy
• Autor: Bojan Jerbić
• Autor: Bojan Šekoranja
• Autor: Filip Šuligoj
• Autor: Josip Vidaković
• Autor: Fadi Almahariq
• Autor: Dominik Romić
• Autor: Marina Raguž
• Autorova ustanova: (Klinička bolnica Dubrava)
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet
• Autorova ustanova: Sveučilište u Zagrebu; Fakultet strojarstva i brodogradnje; (Zavod za robotiku i automatizaciju proizvodnih sustava); (Katedra za autonomne sustave i računalnu inteligenciju)
• Znanstveno / umjetničko područje, polje i grana: TEHNIČKE ZNANOSTI; Strojarstvo; Proizvodno strojarstvo
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti; Kirurgija

Sažetak (engleski)

Aims To report the outcomes of robot-assisted brain biopsies performed using a novel RONNA G4 system. The system was developed by a research group from the Faculty
of Mechanical Engineering and Naval Architecture and a
team of neurosurgeons from Dubrava University Hospital,
University of Zagreb School of Medicine.
Methods This prospective study included 49 biopsies
analyzed during one year: 23 robotic frameless and 26
frame-based Leksell stereotactic biopsies. We analyzed the
presenting symptoms, tumor range and location, postoperative complications, pathohistological diagnosis, diagnostic yield, as well as operation and hospitalization duration. The target point error was calculated to assess the
accuracy of the RONNA system.
Results No postoperative mortality, morbidity, or infections were observed. In the frameless robotic biopsy
group, only one pathohistological diagnosis was inconclusive. Therefore, the diagnostic yield was 95.6% (22/23),
similar to that of the framebased Leksell stereotactic biopsy group (95.1% or 25/26). The average target point error
in the frameless robotic biopsy group was 2.15±1.22 mm
(range 0.39-5.85).
Conclusion The RONNA G4 robotic system is a safe and
accurate tool for brain biopsy, although further research
warrants a larger patient sample, comparison with other
robotic systems, and a systematic analysis of the entry and
target point errors

• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran - međunarodna recenzija
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Croatian Medical Journal
• Brojčani podaci: vol. 62, br. 4, str. 318-327
• p-ISSN: 0353-9504
• e-ISSN: 1332-8166
• DOI: https://doi.org/10.3325/cmj.2021.62.318
• URN:NBN: urn:nbn:hr:235:606495
• Datum objave publikacije: 2021
• URL dokumenta: https://hrcak.srce.hr/278145
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2024-07-03 04:55:15