Rekonstrukcija geometrije koronarne arterije iz CT snimke

undergraduate thesis

• Title (english): Coronary artery geometry reconstruction from CT scan
• Author: Manuel Krajcar
• Mentor: Željko Tuković (mentor)
• Mentor: Zdravko Virag (komentor)
• Granter: University of Zagreb; Faculty of Mechanical Engineering and Naval Architecture; Zagreb
• Defense date and country: 2021-02-25, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Basic Technical Sciences; Fluid Mechanics

Abstract

Razvojem računala i novih algoritama sve je učestalija primjena numeričkih metoda poput metode konačnih elemenata (MKE) i metode konačnih volumena (MKV) u području biomehanike i mehanike bioloških strujanja. Numeričke analize strujanja u krvožilnom sustavu uz medicinske pretrage daju više informacija i omogućuju precizniju dijagnostiku kardiovaskularnih bolesti. Ateroskleroza je bolest arterija koja uzrokuje formiranje plaka nakupljanjem masnoća na unutarnjoj stijenki. Kod ateroskleroze koronarnih arterija suženje poprečnog presjeka veće od 75% može dovesti do srčanog udara. Dijagnosticiranje i provođenje numeričke analize ne bi bilo moguće bez precizne rekonstrukcije geometrije koronarnih arterija oboljelog pacijenta.
U ovom radu opisana je rekonstrukcija geometrije koronarnih arterija dvaju pacijenata na temelju CT koronarografskih snimaka. Iz rekonstruirane geometrije formirana je prostorna domena strujanja te je provedena njena diskretizacija i numerička analiza strujanja.
Rekonstrukcija je provedena u programima 3DSlicer i Blender dok je proračunska mreža napravljena u programu cfMesh. Proračun je proveden pomoću programskog paketa OpenFOAM, a rezultati su obrađeni programom Paraview.

Abstract (english)

With the development of computers and new algorithms, the application of numerical methods such as the finite element method (FEM) and the finite volume method (FEM) in the field of biomechanics and mechanics of biological flows is becoming more frequent. Numerical analyzes of the flow in the vascular system in addition to medical tests provide more information and allow a more accurate diagnosis of cardiovascular diseases. Atherosclerosis is a disease of the arteries that causes plaque to form by the accumulation of fat on the inner wall. In atherosclerosis of the coronary arteries, narrowing of the cross section by more than 75% can lead to a heart attack. Diagnosing and performing numerical analysis would not be possible without a precise reconstruction of the geometry of the coronary arteries of a diseased patient.
This thesis describes the reconstruction of the coronary artery geometry of two patients from CT coronarographic images. Based on the reconstructed geometry, the spatial domain of the flow is defined and discretised and numerical analysis of the flow was performed.
The reconstruction was carried out in 3DSlicer and Blender while mesh is made in cfMesh. The calculation was performed using the OpenFOAM software package, and the results were processed with the Paraview program.

• Keywords: računalna dinamika fluida; koronarne arterije; hemodinamika; strujanje krvi
• Keywords (english): computer fluid dynamics; coronary arteries; hemodynamics; blood flow
• Language: croatian
• URN:NBN: urn:nbn:hr:235:222329
• Study programme: Title: Mechanical Engineering; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka strojarstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka strojarstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-02-21 12:38:14