Numeričko optimiranje geometrije kolagena za 3D ispis

master's thesis

• Title (english): Numerical shape optimization of collagen for 3D printing
• Author: Toni Škugor
• Mentor: Igor Karšaj (mentor)
• Granter: University of Zagreb; Faculty of Mechanical Engineering and Naval Architecture; Zagreb
• Defense date and country: 2018-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Mechanical Engineering

Abstract

Razvoj moderne medicine sve više se oslanja na primjenu inženjerskih znanja i istraživanje u području biomehanike. Upotreba numeričkih metoda, poput metode konačnih elemenata i računalne dinamike fluida te korištenje računalnih simulacija uvelike doprinosi napretku u istraživanju i razumijevanju ponašanja bioloških sustava. Tehnologija aditivne proizvodnje, poznatija kao 3D ispis, osigurava brzu izradu prototipnih modela te eksperimentalno ispitivanje i provjeru numeričkih modela. Jedno od područja istraživanja biomehanike je krvožilni sustav te bolesti vezane uz njega. Sa stajališta mehaničkih svojstava, glavni konstituenti stijenke arterija su kolagenska vlakna i elastinska matrica. U ovom radu, njihova mehanička svojstva nastoje se oponašati upotrebom dva elastomerna materijala. U radu je dan pregled utjecaja različitih parametara na geometriju, a posljedično i mehanička svojstva elastomernih materijala. Prikazan je postupak njihova optimiranja za izradu epruvete putem 3D ispisa. Također prikazana je i usporedba ponašanja elastomernih materijala sa stvarnom stijenkom arterije na primjeru cilindrične geometrije. Za izradu CAD modela korišten je programski paket Catia V5R20 dok su numeričke analize provedene u programskom paketu Abaqus.

Abstract (english)

Nowadays, development of modern medicine is enhanced with use of engineering knowledge and research in the field of biomechanics. Implementation of numerical methods, such as finite element method and computational fluid dynamics with computational simulations is of great contribution in the research processes and understanding of biological systems. Additive manufacturing, also called 3D printing, assures quick production of prototypes and their experimental testing and validation. One of research areas in biomechanics is cardiovascular system and its diseases. From mechanical point of view, the most important constituents of arteries are collagen fibers and elastin matrix. In this thesis, their mechanical properties are being mimicked by using two elastomer materials. This thesis contains overview of effects on mechanical properties caused by changing geometry of collagen fiber mimic. Process of optimization is carried out for design of uniaxial tension testing specimen with 3D printing technology. In addition, comparison between cylindrical geometry elastomer model and really artery wall is presented. CAD models are created with software Catia V5R20 and numerical analysis is carried out in Abaqus software.

• Keywords: metoda konačnih elemenata; arterije; aditivna proizvodnja; hiperelastičnost
• Keywords (english): finite element method; arteries; additive manufacturing; hyperelasticity
• Language: croatian
• URN:NBN: urn:nbn:hr:235:672183
• Study programme: Title: Mechanical Engineering; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra inženjer/inženjerka strojarstva (magistar/magistra inženjer/inženjerka strojarstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-05-22 22:39:40