Analiza proizvodnog procesa u pogonu za tabletiranje

master's thesis

• Title (english): Analysis of the production process in the tableting facility
• Author: Tomislav Barun
• Mentor: Hrvoje Cajner (mentor)
• Committee member: Ivica Garašić (predsjednik povjerenstva)
• Granter: University of Zagreb; Faculty of Mechanical Engineering and Naval Architecture; Zagreb
• Defense date and country: 2024-12-05, Croatia
• Scientific / art field, discipline and subdiscipline: TECHNICAL SCIENCES; Mechanical Engineering; Production Mechanical Engineering

Abstract

Optimizacija proizvodnih procesa ključan je izazov farmaceutske industrije koja se suočava s rastućim zahtjevima za učinkovitošću, kvalitetom i usklađenošću s regulatornim normama. Ovaj je rad usmjeren na analizu unaprjeđenja procesa tabletiranja suhih oralnih oblika u specifičnom proizvodnom pogonu, s ciljem povećanja operativne učinkovitosti. Korištenjem metodologije kontinuiranog poboljšanja, rad se fokusira na unapređenje prijelaza i standardizaciju postupaka, što pridonosi smanjenju zastoja i povećanju proizvodne kvalitete. Rad je strukturiran kroz analizu trenutnog stanja, identifikaciju ključnih problema, te razvoj i evaluaciju prijedloga za unaprjeđenje.

Abstract (english)

Optimization of production processes is a critical challenge for the pharmaceutical industry, which faces increasing demands for efficiency, quality, and compliance with regulatory standards. This paper focuses on analyzing improvements in the tablet manufacturing process for solid oral dosage forms in a specific production facility, with the goal of enhancing operational efficiency. By applying continuous improvement methodology, the work emphasizes the optimization of changeovers and standardization of procedures, contributing to reduced downtime and improved production quality. The paper is structured through an analysis of the current state, identification of key issues, and the development and evaluation of proposals for improvement.

• Keywords: farmaceutska industrija; tabletiranje; unapređenje; prijelazi; zastoji; SMED; standardizacija; uštede
• Keywords (english): pharmaceutical industry; tableting; improvement; changeovers; downtime; SMED; standardization; savings
• Language: croatian
• URN:NBN: urn:nbn:hr:235:089757
• Study programme: Title: Mechanical Engineering; specializations in: Design, Process and Energy Engineering, Production Engineering, Engineering Modelling and Computer Simulation, Marine Engineering, Industrial Engineering and Management, Materials Engineering, Mechanics and Robotics, Autonomous Systems, Mechatronics and Robotics; Course: Industrial Engineering and Management; Study programme type: university; Study level: graduate; Academic / professional title: sveučilišni/a magistar/magistra inženjer/inženjerka strojarstva (sveučilišni/a magistar/magistra inženjer/inženjerka strojarstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Embargoed access; Embargo expiration date: 2026-11-28
• Created on: 2024-12-04 10:39:00